Article 2222

Title of the article

The effect of SARS-CoV-2 infection on structural and functioal properties of arteries 

Authors

Irina V. Avdeeva, Candidate of medical sciences, associate professor оf the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: eliseeva.iv1@gmail.ru
Kristina N. Polezhaeva, Postgraduate student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: hristinamack4rova@yandex.ru
Nadezhda V. Burko, Candidate of medical sciences, associate professor оf the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: hopeful.n@mail.ru
Angelina A. Khromova, Candidate of medical sciences, associate professor оf the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: hromova-a.a@yandex.ru
Yuliya A. Tomashevskaya, Candidate of medical sciences, associate professor оf the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: t.julia74@mail.ru
Valentin E. Oleynikov, Doctor of medical sciences, professor, head of the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: v.oleynikof@gmail.com 

Abstract

Background. The causative agent of SARS-CoV-2 coronavirus infection, in addition to the known effect on the respiratory system, has a pronounced destructive effect on the vascular bed. The purpose of this study is to evaluate the structural and functional properties of the large arteries in patients who had undergone COVID-19. Materials and methods. 62 people were examined, who were divided into 2 groups: the first group included 32 healthy volunteers, the second group consisted of 30 people who had suffered COVID-19. The arterial stiffness was evaluated using the method of applanation tonometry and volume sphygmography. The local stiffness of the common carotid arteries (CCA) was studied using the ultrasound with high-frequency RF signal technology. The state of the endothelium was studied by the method of flow-mediated dilation (FMD). Results. The data obtained in this study reflect the relationship between the presence of SARS-CoV-2 infection and the negative change in most parameters reflecting the structural and functional state of the arteries. Conclusions. By initiating vascular aging earlier, COVID-19 infection has adverse consequences for the structure and function of the arteries, and, as a consequence, for the cardiovascular prognosis in those who have been ill. 

Key word

SARS-CoV-2, COVID-19, endothelial dysfunction, arterial stiffness, early vascular aging 

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For citation:

Avdeeva I.V., Polezhaeva K.N., Burko N.V., Khromova A.A., Tomashevskaya Yu.A., Oleynikov V.E. The effect of SARS-CoV-2 infection on structural and functioal properties of arteries. Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2022;(2):14–25. (In Russ.). doi:10.21685/2072-3032-2022-2-2

 

Дата создания: 22.06.2022 08:35
Дата обновления: 22.11.2022 13:14